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Bioprocess Engineering Design

Journal Articles:

  • Harding, KG; Dennis, JS; Harrison, STL.  2018.  Generic flowsheeting approach to generating first estimate material and energy balance data for Life Cycle Assessment (LCA) of Penicillin V production.  Sustainable Production and Consumption 15 (2018) 89–95.
  • Naidoo, M; Tai, SL; Harrison, STL. 2018. Energy requirements for the in-situ recovery of biobutanol via gas stripping. Biochemical Engineering Journal 139 (2018) 74–84.
  • Nosrati-Ghods N., Harrison S.T.L., Isafiade A.J. and Tai S.L. (2018). Ethanol from Biomass Hydrolysates by Efficient Fermentation of Glucose and Xylose – A Review.  ChemBioEng Reviews 5 (5) 294-311., KG; Harrison, STL. 2016. Generic flow sheet model for early inventory estimates of industrial microbial processes. I. Flowsheet development, microbial growth and product formation, South African Journal of Chemical Engineering, Volume 22, Pages 34-43.
  • Harding, KG; Harrison, STL. 2016. Generic flowsheet model for early inventory estimates of industrial microbial processes. II. Downstream processing. South African Journal of Chemical Engineering, Volume 22, Pages 23-33.
  • Meissner M.P., Xu Z., Jones G.C., Minnaar S.H. and Harrison S.T.L. (2014). A novel microwell-based analytical technique for studying ferrous iron biooxidation activity. Minerals Engineering 60: 8-13. [Impact factor 1.352].
  • Olaofe OA, Fenner CJ, Gudiminchi RK, Smit MS, Harrison STL. (2013). The influence of microbial physiology on biocatalyst activity and efficiency in the terminal hydroxylation of n-octane using Escherichia coli expressing the alkane hydroxylase, CYP153A6. Microbial Cell Factories (2013) 12:8: 1-12.
  • Harrison STL, Stevenson R and Cilliers JJ. 2012. Assessing solids concentration homogeneity in Rushton-agitated slurry reactors using electrical. Chemical Engineering Science (2012) 71: 392-399.
  • Langley NM, Harrison STL and Van Hille RP. 2012. A critical evaluation of CO2 supplementation to algal systems by direct injection. Biochemical Engineering Journal (2012) 68: 70– 75.
  • Sheridan C, Petersen J and Rohwer J. 2012. On modifying the Arrhenius equation to compensate for temperature changes for reactions within biological systems .Water SA (2012) 38:1 149-151.
  • Gudiminchi RK, Randall C, Opperman DJ, Olaofe OA, Harrison STL, Albertyn J and Smit MS. Whole-cell hydroxylation of n-octane by Escherichia coli strains expressing the CYP153A6 operon. Applied Microbiology and Biotechnology (December 2012) 96:6: 1507-1516.
  • Bryan CG, Davis-Belmar CS, Van Wyk N, Fraser MK, Dew D, Rautenbach GF and Harrison STL. (2012). The Effect of CO2 Availability on the Growth, Iron Oxidation and CO2-Fixation Rates of Pure Cultures of Leptospirillum ferriphilum and Acidithiobacillus ferrooxidans. Biotechnology and Bioengineering (2012) 109:7: 1693-1703.
  • Harrison Susan T. L, Stevenson Ryan; Cilliers Johannes J. (2012). Assessing solids concentration homogeneity in Rushton-agitated slurry reactors using electrical.Chemical Engineering Science, Volume: 71 Pages: 392-399.
  • Stevenson R, Harrison S T L, Mantle M D, Sederman A J, Moraczewski T L and Johns M L. (2010). Analysis of partial suspension in stirred tanks using MRI and ERT. Chemical Engineering Science 65 (4), 1385 - 1393.
  • Olaofe O, Burton S.G., Cowan D.A. and Harrison S.T.L. (2010). Improving the production of a thermostable amidase through optimising IPTG induction in a highly dense culture of recombinant E.coli. Biochemical Engineering Journal 52, 19-24.
  • Kirby, B.; Vengadajellum, C.J.; Burton, S.G. and Cowan, D.A. (2009). Handbook of hydrocarbon microbiology: Microbial interactions with hydrocarbons, oils, fats and related hydrophobic substrates and products. Kenneth N. Timmis (Ed) Springer Verlag
  • Harding K G, Harrison S T L, Dennis J S and von Blottnitz H. (2008) A life cycle comparison between inorganic or biological catalytic process routes for the production of biodiesel. J. Cleaner Production 16 (13), 1368-1378. [Impact factor 0.762].
  • Oborien B O, Vengadajellum C J, Burton S G, Cowan D A and Harrison S T L (2008). The effect of the particulate phase on coal biosolubilisation mediated by Trichoderma atroviride in a slurry bioreactor. Fuel Processing Technology 89 (2), 123-130.
  • Harding K G, Dennis J S, von Blottnitz H and Harrison S T L (2007). Environmental analysis of plastic production processes: comparing petroleum based polypropylene and polyethylene with biologically based poly--hydroxybutyric acid using life cycle analysis. Journal of Biotechnology, 130 (1), 57 – 66.
  • Silva-Stenico, M.; Vengadajellum, C.J.; Janjua, H.A.; Harrison, S.T.L.; Burton, S.G. and Cowan, D.A. (2007) Degradation of low rank coal by Trichoderma actroviride ES 11. J. Ind. Microbiol. Biotechnol 34 (9): 625-631
  • Clarke K.G., Williams P.C., Smit M. and Harrison S.T.L. (2006). Enhancement and repression of volumetric oxygen transfer coefficient through hydrocarbon addition and its influence on oxygen transfer rate in stirred tank bioreactors.Biochemical Engineering Journal 28, 237-242
  • Stevenson R, Harrison STL, Miles N and Cilliers JJ (2006). Examination of swirling flow using electrical resistance tomography. Powder Technology 162, 157-165.
  • Robinson A. and Harrison S T L (2001). Effect of aeration in propagation on surface properties of Brewers' yeast. Applied Microbiology Volume 2 Focus on Biotechnology (ed. Durieux and J-P Simon). Dordrecht, Kluwer. Academic Publishers. 2, 89-99.
  • Robinson A and Harrison STL (2001) Disk stack centrifugation for the Recovery of Brewers’ yeast: Its Effect on Yeast Cell Surface, Flocculation and Fermentation Performance. Proceedings of the Institute and Guild of Brewing Convention 8, 157-164.
  • Illing S and Harrison S T L (1999). The kinetics and mechanism of Corynebacterium glutamicum aggregate breakup in bioreactors. Chem. Eng. Sci.., 54, 441-454.
  • Cilliers J J and Harrison S T L. (1997). The application of mini-hydrocyclones in the concentration of microbial suspensions. The Chemical Engineering Journal, 65, 21-26.
  • Harrison S T L and Cilliers J J. (1997). The use of mini-hydrocyclones for differential separations within mineral slurries subjected to bioleaching. Minerals Engineering, 10 (5), 529-535.
  • Basson L., Robinson A., Godfrey T.A., O’Connor-Cox E., Axcell B. and Harrison S.T.L. (1997). Mechanical handling of brewers’ yeast during cropping and its effect on yeast quality. Proc. Inst. Brew. Conv. (Central & Southern African sections), 6, 55-60
  • Scholtz N J, Pandit A B and Harrison S T L (1997). Effect of solids suspension on microbial cell disruption. Bioreactor & Bioprocess Fluid Dynamics, (ed. A W Nienow), pp 199 - 215.
  • Harrison S.T.L and Mackley M.R. (1992). A pulsatile flow bioreactor. Chemical Engineering Science, 47 (2), 490-493.
  • Largier S.T., Long S, Santangelo J.D., Jones D.T. and Woods D.R. (1985). Immobilised Clostridium acetobutylicum P262 mutants for solvent production. Appl. Environ. Microbiol., 50, 477-481.

Book Chapters: 

  • Harrison, STL. 2016. Biotechnologies that Use Acidophiles. In Quatrini, R; Johnson, DB. Acidophiles: Life in Extremely Acidic Environments. Caister Academic Press. pp 265-284.